NF-κB-IN-9

CAT: 0804-HY-149838Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-149838Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

NF-κB-IN-9 is a nuclear factor kappa B (NF-κB) targeting sonosensitizer (λex/λem=489/628 nm) . NF-κB-IN-9 exhibits strong inhibition on NF-κB signaling due to its two resveratrol units in one molecule. NF-κB-IN-9 has anti-tumor activity and shows remarkable sonocytotoxicity against cancer cells. NF-κB-IN-9 has biosafety in eenograft mice model.

CAS Number

3033815-24-3

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nf-κb-in-9.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(OC)=CC(/C=C/C2=CC=C(C=C2)N(C3=CC=CC=C3)C4=CC=C(C=C4)C5=CC=C(C6=NSN=C65)C7=CC=C(C=C7)N(C8=CC=CC=C8)C9=CC=C(C=C9)/C=C/C%10=CC(OC)=CC(OC)=C%10)=C1

Molecular Formula

C62H50N4O4S

Molecular Weight

947.15

References & Citations

[1]Li Y, et al. Design of Sonosensitizers Integrated with Resveratrol Motif for Synergetic Sonodynamic Therapy and Nuclear Factor Kappa B Transcription Suppression of Breast Cancer. J Med Chem. 2023 Apr 19.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-144765-01	NF-κB-IN-4
HY-175833	NF-κB-IN-20
HY-158156	NF-κB-IN-16
HY-144744	NF-κB-IN-3
HY-149248	NF-κB-IN-8
HY-149580	NF-κB-IN-12
HY-162004	NF-κB-IN-14
HY-126026	NF-κB-IN-17
HY-138537-01	NF-κB-IN-1
HY-147770	NF-κB-IN-6

Alternative Products

Catalog	Name
GTR19220871-01	NF-κB-IN-9
MBS5816777	NF-kappaB-IN-9
sc-137009	NF-H (D-9)
sc-398532	NF-M (E-9)
60614	NF-κB Reporter Kit (NF-κB Signaling Pathway)
BA8604-1	NF-κB-IN-1
T208821-01	NF-κB-IN-14
T89612-01	NF-κB-IN-17
T62060-01	NF-κB-IN-5
T78750-01	NF-κB-IN-10

NF-κB-IN-9

Related Products

Alternative Products

Popular Products