NF-?B-IN-5

• Target :

  Others|||Apoptosis|||NF-?B

• Related Pathways :

  Others|||NF-?B|||Apoptosis

• Bioactivity :

  NF-?B-IN-5 (compound 4d) is an orally active NF-?B inhibitor that interacts directly with NF-?B, and exhibits antitumor activity against human cancer cell lines, with IC50 values of 5.35, 2.81, 2.83, 2.02, and 3.90 ?M for HCT116, U87-MG, HepG2, BGC823, and PC9, respectively.

• Smiles :

  C[C@]12[C@@]([C@@]3([C@](C(=C)C(=O)O3)(CC/C(/C=N/NC(NC4=CC=C(C)C=C4)=O)=C\CC1)[H])[H])(O2)[H]

• Molecular Formula :

  C23H27N3O4

• Molecular Weight :

  409.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2425675-52-9