NF-κB-IN-6

NF-κB-IN-6

• UNSPSC Description: NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent through the mechanism of decreasing the protein expressions of iNOS and COX-2 by suppressing NF-κB signaling pathway. NF-κB-IN-6 inhibits NO production in LPS-induced RAW264.7 cells with an IC50 of 23.1 μM[1].
• Target Antigen: NF-κB
• Type: Reference compound
• Related Pathways: NF-κB
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/nf-κb-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: [H][C@]12CC=C(CO)[C@@]1([H])C3N(C)CCN3C=C2C(OC)=O
• Molecular Weight: 264.32
• References & Citations: [1]Li SM, et al. Bioactivity Study of Tricyclic and Tetracyclic Genipin Derivatives as Anti-inflammatory Agents. Bioorg Chem. 2022 Sep;126:105881.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported