NF-κB-IN-6

CAT: 0804-HY-147770Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-147770Size:1 Each

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Description

NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent through the mechanism of decreasing the protein expressions of iNOS and COX-2 by suppressing NF-κB signaling pathway. NF-κB-IN-6 inhibits NO production in LPS-induced RAW264.7 cells with an IC50 of 23.1 μM[1].

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nf-κb-in-6.html

Solubility

10 mM in DMSO

Smiles

[H][C@]12CC=C(CO)[C@@]1([H])C3N(C)CCN3C=C2C(OC)=O

Molecular Formula

C14H20N2O3

Molecular Weight

264.32

References & Citations

[1]Li SM, et al. Bioactivity Study of Tricyclic and Tetracyclic Genipin Derivatives as Anti-inflammatory Agents. Bioorg Chem. 2022 Sep;126:105881.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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HY-149580	NF-κB-IN-12
HY-162004	NF-κB-IN-14
HY-126026	NF-κB-IN-17
HY-138537-01	NF-κB-IN-1

Alternative Products

Catalog	Name
GTR19188043-01	NF-κB-IN-6
sc-8008 B	NFκB p65 (F-6) B
sc-166588	NFκB p50 (D-6)
sc-8008	NFκB p65 (F-6)
sc-166588 HRP	NFκB p50 (D-6) HRP
sc-8008 TRITC	NFκB p65 (F-6) TRITC
sc-166588 PE	NFκB p50 (D-6) PE
sc-166588 FITC	NFκB p50 (D-6) FITC
sc-8008 X	NFκB p65 (F-6) X
sc-8008 AC	NFκB p65 (F-6) AC

NF-κB-IN-6

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