Products for Research Use Only
RegisterLogin

PDE4-IN-5

CAT: 0804-HY-144265Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-144265Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PDE4-IN-5 (compound 33a) is a potent and selective PDE4 inhibitor (IC50=3.1 nM) . PDE4-IN-5 has favorable skin permeability and a well-characterized binding mechanism. Anti-psoriasis effect[1].
CAS Number
2768626-06-6
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pde4-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=NC(C)=CC=C2C3=C1[C@@H](C[C@@](C)(O3)CCO)/C=C(C)\C)CC
Molecular Formula
C21H28N2O3
Molecular Weight
356.46
References & Citations
[1]Song Z, et al. Discovery and Structural Optimization of Toddacoumalone Derivatives as Novel PDE4 Inhibitors for the Topical Treatment of Psoriasis. J Med Chem. 2022;65 (5) :4238-4254.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4

Related Products

CatalogName
HY-169981PDE4-IN-24
HY-162583PDE4-IN-17
HY-132887PDE4-IN-3
HY-151174PDE4-IN-12
HY-161381PDE4-IN-15
HY-115871PDE4-IN-4
HY-179639PDE4-IN-30
HY-W787896-01PDE4-IN-25
HY-W186242-01PDE4-IN-16
HY-144684PDE4-IN-8

Alternative Products

CatalogName
T61295-01PDE4-IN-5
BA8215-10PDE4-IN-14
T211159-01PDE4-IN-29
T210960-01PDE4-IN-28
T210238-01PDE4-IN-17
T200132-01PDE4-IN-19
T62969-01PDE4-IN-6
T60934-01PDE4-IN-9
T63912-01PDE4-IN-12
T50023-01PDE4-IN-20

Popular Products