BRD4 D1-IN-2

BRD4 D1-IN-2

• CAS Number: 2863687-22-1
• UNSPSC Description: BRD4 D1-IN-2 (compound 26) is a potent and selective BRD4 D1 inhibitor (IC50[1].
• Target Antigen: Epigenetic Reader Domain
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/brd4-d1-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C1=CC=C(C(OC2=NC(C3=C(N=CN3C4CCN(CC4)CCN(C)C)C5=CC=C(C=C5)C(F)(F)F)=CC=N2)=C1)C)C
• Molecular Weight: 592.70
• References & Citations: [1]Cui H, et al. A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem. 2022;65(3):2342-2360.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported