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PLK1/BRD4-IN-2

CAT: 0931-T87220-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87220-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2251709-89-2
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
PLK1/BRD4-IN-2 (compound 15), an analog of BI-2536, simultaneously inhibits both Polo-like kinase 1 (PLK1 IC 50 = 40 nM) and BRD4 bromodomain (BRD4-BD1 IC 50 = 28 nM) as a dual inhibitor [1].
Smiles
C[C@H]1N(C=2C(N(C)C1=O)=CN=C(NC3=C(OC)C=C(C(=O)N4CCCCCC4)C=C3)N2)C5CCCC5
Molecular Formula
C27H36N6O3
Molecular Weight
492.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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HY-160557-01PLK1/BRD4-IN-2
HY-160558-01PLK1/BRD4-IN-3
GTR19185523-01PLK1/BRD4-IN-1
HY-158031-01PLK1/BRD4-IN-5
GTR19189468BRD4-IN-2
GTR19188572PLK1-IN-2
C8457-250BRD4-BD1-IN-2
HY-150613PARP1/BRD4-IN-2
sc-518158BRD4 (C-2)
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