BRD4-IN-2

• Description :

  BRD4-IN-2 is a bromodomain BRD4 inhibitor with an IC50 value of 9.9 nM.

• CAS Number :

  [2679925-55-2]

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/brd4-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CNC(N1N=C(C2=C(C[C@@H]1C)C=C(C(OC)=C2)OC)C3=CC=C(C=C3)N4CCN(CC4)C(COCCOCC(NC5=C6C(N(C(C6=CC=C5)=O)C7CCC(NC7=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C43H48N8O11

• Molecular Weight :

  852.89

• References & Citations :

  [1]Sabnis RW. Substituted 2,3-Benzodiazepines Derivatives as Bromodomain BRD4 Inhibitors. ACS Med Chem Lett. 2021 Sep 28;12 (10) :1530-1531.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported