BRD4 D1-IN-1

• UNSPSC Description:

  BRD4 D1-IN-1 is a selective BRD4 D1 inhibitor (IC50[1].

• Target Antigen:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/brd4-d1-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(C(OC2=NC(C3=C(N=CN3[C@@H]4CN(CC4)CCN(C)C)C5=CC=C(C=C5)C(F)(F)F)=CC=N2)=C1)C)C

• Molecular Weight:

  578.67

• References & Citations:

  [1]Cui H, et al. A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem. 2022;65(3):2342-2360.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2863623-98-5