WIZ degrader 2

• UNSPSC Description:

  WIZ degrader 2 (Compound 142) is a degrader for widely interspaced zinc finger motifs with an AC50 of 0.011 μM. WIZ degrader 2 induces the expression of fetal hemoglobin (HbF) with an EC50 of 0.038 μM. WIZ degrader 2 can be used in research about inherited blood disorders[1].

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/wiz-degrader-2.html

• Smiles:

  O=C(NC(CC1)=O)N1C(C=NN2C=C3)=C2C=C3C[C@H]4C[C@@H](N(CC4)CC5CCOCC5)C

• Molecular Weight:

  439.55

• References & Citations:

  [1]BONAZZI S, et al., Pyrazolopyridine derivatives and uses thereof. WO2022195454A1

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2839552-69-9