VAV1 degrader-2

VAV1 degrader-2

• CAS Number: 3050683-29-6
• UNSPSC Description: VAV1 degrader-2 (Example 176) is a molecular glue degrader based on targeting VAV 1 with a DC50 of 4.41 nM. VAV1 degrader-2 can be used in the study of inflammatory and autoimmune diseases[1].
• Target Antigen: Molecular Glues
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/vav1-degrader-2.html
• Smiles: ClC1=C(C2CCC(NC2=O)=O)C=CC=C1C3=CC=C(CC4=NN(C)C=C4)C=C3
• Molecular Weight: 393.87
• References & Citations: [1]Laura Ann Mcallister, et al. Targeted degradation of vav1. WO2024151547A1. 2024-01-08
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported