VAV1 degrader-2

• UNSPSC Description:

  VAV1 degrader-2 (Example 176) is a molecular glue degrader based on targeting VAV 1 with a DC50 of 4.41 nM. VAV1 degrader-2 can be used in the study of inflammatory and autoimmune diseases[1].

• Target Antigen:

  Molecular Glues

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/vav1-degrader-2.html

• Smiles:

  ClC1=C(C2CCC(NC2=O)=O)C=CC=C1C3=CC=C(CC4=NN(C)C=C4)C=C3

• Molecular Weight:

  393.87

• References & Citations:

  [1]Laura Ann Mcallister, et al. Targeted degradation of vav1. WO2024151547A1. 2024-01-08

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3050683-29-6