ERα degrader-2

CAT: 0931-T39727Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T39727Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2235396-63-9

Target

ERK, Estrogen Receptor/ERR

Related Pathways

Endocrinology/Hormones, MAPK

Purity

0.9971

Bioactivity

ERα degrader-2 is a selective and potent estrogen receptor (SERD) degrader with anticancer activity, exhibiting an EC50 value of 0.3 nM for ERα degradation. It can be used for the prevention and treatment of HER-positive breast cancer.

Smiles

[H][C@@]1(N(CC(C)(C)F)[C@H](C)Cc2c1[nH]c1ccccc21)c1c(F)cc(cc1F)-c1ccc(cc1)C(O)=O

Molecular Formula

C29H27F3N2O2

Molecular Weight

492.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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ERα degrader-2

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