IKZF1-degrader-1

• UNSPSC Description:

  IKZF1-degrader-1 (Compound 9-B) is a IKZF1 molecular glue degrader with the DC50 value of 0.134 nM. IKZF1-degrader-1 can be used to degrader tumors[1].

• Target Antigen:

  IKZF Family; Molecular Glues

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ikzf1-degrader-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N([C@@H]2C(NC(CC2)=O)=O)C3=CC=C(C4=CC(F)=CC1=C43)CC5=CC=C(C=C5)CN6CCN(C7=C(C=C(C=C7)C#N)F)CC6

• Molecular Weight:

  605.63

• References & Citations:

  [1]Li qiamg Fu, et al. Isoindolinone compound and use thereof. Publication of WO2023025112A1. 2023-03-02.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2915586-02-4