GSPT1 degrader-2

GSPT1 degrader-2

• CAS Number: 2803879-60-7
• UNSPSC Description: GSPT1 degrader-2 (Compound 210) is a potent and orally active GSPT1 molecular glue degrader (DC50: [1].
• Target Antigen: DNA/RNA Synthesis; Molecular Glues
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/gspt1-degrader-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC(CC1)=O)C1N2CC(C=CC(COC(NC3=CC(Cl)=C(C)C=C3)=O)=C4)=C4C2=O
• Molecular Weight: 441.86
• References & Citations: [1]Gerald GAVORY, et al. Treatment of myc-driven cancers with gspt1 degraders. Patent. WO2022152822.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported