GSPT1 degrader-2

• UNSPSC Description:

  GSPT1 degrader-2 (Compound 210) is a potent and orally active GSPT1 molecular glue degrader (DC50: [1].

• Target Antigen:

  DNA/RNA Synthesis; Molecular Glues

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/gspt1-degrader-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC(CC1)=O)C1N2CC(C=CC(COC(NC3=CC(Cl)=C(C)C=C3)=O)=C4)=C4C2=O

• Molecular Weight:

  441.86

• References & Citations:

  [1]Gerald GAVORY, et al. Treatment of myc-driven cancers with gspt1 degraders. Patent. WO2022152822.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2803879-60-7