CK1α degrader-1

• CAS Number:

  2881012-96-8

• UNSPSC Description:

  CK1α degrader-1 (Compound 82) is an orally active CK1α degrader with a DC50 of 0.105 μM. CK1α degrader-1 can be used for the research of cancer[1].

• Target Antigen:

  Casein Kinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ck1α-degrader-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=CC=C(C(N[C@H](C3=CC=C(C=N3)Cl)C4CCC4)=O)C=C2CN1[C@@H]5C(NC(CC5)=O)=O

• Molecular Weight:

  466.92

• References & Citations:

  [1]Fu L, et al. Isoindolinone compounds, and uses thereof. WO2022257897A1. 2022-12-15.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported