CK1α degrader-1

CK1α degrader-1

• CAS Number: 2881012-96-8
• UNSPSC Description: CK1α degrader-1 (Compound 82) is an orally active CK1α degrader with a DC50 of 0.105 μM. CK1α degrader-1 can be used for the research of cancer[1].
• Target Antigen: Casein Kinase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ck1α-degrader-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=CC=C(C(N[C@H](C3=CC=C(C=N3)Cl)C4CCC4)=O)C=C2CN1[C@@H]5C(NC(CC5)=O)=O
• Molecular Weight: 466.92
• References & Citations: [1]Fu L, et al. Isoindolinone compounds, and uses thereof. WO2022257897A1. 2022-12-15.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported