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ER degrader 9

CAT: 0804-HY-163812Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163812Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ER degrader 9 (compound 1), a bifunctional molecular glue, is a potent estrogen receptor (ER) degrader with a DC50 of ≤10 nM in MCF-7 cells. ER degrader 9 can be used for the research of breast cancer[1].
CAS Number
3023359-75-0
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Molecular Glues
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/er-degrader-9.html
Smiles
CC(C)(/C=C(C(N1CCN(CC1)CC2CCN(CC2)C3=CC=C(C=C3)[C@H]4[C@H](CCC5=CC(O)=CC=C54)C6=CC=CC=C6)=O)/C#N)C
Molecular Formula
C40H48N4O2
Molecular Weight
616.83
References & Citations
[1]Andrea TESTA, et al. Bifunctional molecules for targeted protein degradation. WO2023242598A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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