Nrf2 activator-12

Nrf2 activator-12

• CAS Number: 3020661-05-3
• UNSPSC Description: Nrf2 activator-12 (compund 10v) potently activates Nrf2 (EC50=83.5 nM) and exhibits promising pharmacological properties, reversing disease progression and alleviating demyelination in an experimental autoimmune encephalomyelitis mouse model[1].
• Target Antigen: Keap1-Nrf2
• Type: Reference compound
• Related Pathways: NF-κB
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/nrf2-activator-12.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: ClC1=CC=CN=C1S(=N)(/C=C/C2=CC=CC=C2Cl)=O
• Molecular Weight: 313.20
• References & Citations: [1]https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01907
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported