Nrf2 activator-12

• UNSPSC Description:

  Nrf2 activator-12 (compund 10v) potently activates Nrf2 (EC50=83.5 nM) and exhibits promising pharmacological properties, reversing disease progression and alleviating demyelination in an experimental autoimmune encephalomyelitis mouse model[1].

• Target Antigen:

  Keap1-Nrf2

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nrf2-activator-12.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  ClC1=CC=CN=C1S(=N)(/C=C/C2=CC=CC=C2Cl)=O

• Molecular Weight:

  313.20

• References & Citations:

  [1]https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01907

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3020661-05-3