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A3AR agonist 4

CAT: 0804-HY-158180Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158180Size:1 Each
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Description
A3AR agonist 4 is an A3 adenosine receptor (A3AR) agonist (Ki: 1.24 nM for hA3AR) . A3AR agonist 4 inhibits cAMP production with an EC50 of 0.17 nM. A3AR agonist 4 can be used for research of inflammation and pain[1].
CAS Number
3032475-23-0
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/a3ar-agonist-4.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@]2(C3=NN(C=N3)C)[C@]([C@@H](N4C5=C(C6=C(C=C(N6)C)C(Cl)=N5)N=C4)[C@@H]1O)([H])C2
Molecular Formula
C18H18ClN7O2
Molecular Weight
399.83
References & Citations
[1]Charles J. Cohen, et al. Adenosine analogs for the treatment of disease. Patent. WO2024064701A2
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A3 receptor (A3R)

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