A3AR agonist 4

A3AR agonist 4

• CAS Number: 3032475-23-0
• UNSPSC Description: A3AR agonist 4 is an A3 adenosine receptor (A3AR) agonist (Ki: 1.24 nM for hA3AR). A3AR agonist 4 inhibits cAMP production with an EC50 of 0.17 nM. A3AR agonist 4 can be used for research of inflammation and pain[1].
• Target Antigen: Adenosine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/a3ar-agonist-4.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@@]2(C3=NN(C=N3)C)[C@]([C@@H](N4C5=C(C6=C(C=C(N6)C)C(Cl)=N5)N=C4)[C@@H]1O)([H])C2
• Molecular Weight: 399.83
• References & Citations: [1]Charles J. Cohen, et al. Adenosine analogs for the treatment of disease. Patent. WO2024064701A2
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported