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A3AR agonist 5

CAT: 0804-HY-158181Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158181Size:1 Each
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Description
A3AR agonist 5 (Compound 6b) is a A3 adenosine receptor (A3AR) activator, with EC50 and Ki values of 0.14 nM and 6.36 nM for cAMP and hA3, respectively. A3AR agonist 5 can be used in pain and inflammatory research[1].
CAS Number
3032475-38-7
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/a3ar-agonist-5.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@]2(C3=NC=CN3)[C@]([C@@H](N4C5=C(C6=C(C=C(N6)C)C(Cl)=N5)N=C4)[C@@H]1O)([H])C2
Molecular Formula
C18H17ClN6O2
Molecular Weight
384.82
References & Citations
[1]Cohen CJ, et al. Adenosine analogs for the treatment of disease. WO2024064701A2. 2024-03-28
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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