A3AR agonist 5

• UNSPSC Description:

  A3AR agonist 5 (Compound 6b) is a A3 adenosine receptor (A3AR) activator, with EC50 and Ki values of 0.14 nM and 6.36 nM for cAMP and hA3, respectively. A3AR agonist 5 can be used in pain and inflammatory research[1].

• Target Antigen:

  Adenosine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/a3ar-agonist-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1[C@@]2(C3=NC=CN3)[C@]([C@@H](N4C5=C(C6=C(C=C(N6)C)C(Cl)=N5)N=C4)[C@@H]1O)([H])C2

• Molecular Weight:

  384.82

• References & Citations:

  [1]Cohen CJ, et al. Adenosine analogs for the treatment of disease. WO2024064701A2. 2024-03-28

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3032475-38-7