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A3AR agonist 3

CAT: 0804-HY-158179Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158179Size:1 Each
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Description
A3AR agonist 3 (Compound 15A) is a A3 adenosine receptor (A3AR) agonist, with Ki and EC50 values of 2.27 and 0.20 nM for hA3 and cAMP, respectivelly. A3AR agonist 3 can be used for the research of neuroinflammation[1].
CAS Number
3032474-53-3
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/a3ar-agonist-3.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H](N2C3=C(C4=C(C=C(N4)C)C(Cl)=N3)N=C2)[C@]5([H])[C@@]([C@H]1O)([H])C5
Molecular Formula
C15H15ClN4O2
Molecular Weight
318.76
References & Citations
[1]Cohen CJ, et al. Adenosine analogs for the treatment of disease. WO2024064701A2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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