A3AR agonist 3

• Description :

  A3AR agonist 3 (Compound 15A) is a A3 adenosine receptor (A3AR) agonist, with Ki and EC50 values of 2.27 and 0.20 nM for hA3 and cAMP, respectivelly. A3AR agonist 3 can be used for the research of neuroinflammation[1].

• UNSPSC :

  12352005

• Target :

  Adenosine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/a3ar-agonist-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@H]1[C@H](N2C3=C(C4=C(C=C(N4)C)C(Cl)=N3)N=C2)[C@]5([H])[C@@]([C@H]1O)([H])C5

• Molecular Formula :

  C15H15ClN4O2

• Molecular Weight :

  318.76

• References & Citations :

  [1]Cohen CJ, et al. Adenosine analogs for the treatment of disease. WO2024064701A2.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3032474-53-3]