A3AR agonist 3

• Description:

  A3AR agonist 3 (Compound 15A) is a A3 adenosine receptor (A3AR) agonist, with Ki and EC50 values of 2.27 and 0.20 nM for hA3 and cAMP, respectivelly. A3AR agonist 3 can be used for the research of neuroinflammation[1].

• UNSPSC:

  12352005

• Target:

  Adenosine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/a3ar-agonist-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@H](N2C3=C(C4=C(C=C(N4)C)C(Cl)=N3)N=C2)[C@]5([H])[C@@]([C@H]1O)([H])C5

• Molecular Formula:

  C15H15ClN4O2

• Molecular Weight:

  318.76

• References & Citations:

  [1]Cohen CJ, et al. Adenosine analogs for the treatment of disease. WO2024064701A2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3032474-53-3]