Impromidine

• Description :

  Impromidine (SKF 92676) is a potent agonist for histamine H2 receptor. Impromidine induces gastric mucosal blood flow and acid secretion[1][2].

• Product Name Alternative :

  SKF 92676

• UNSPSC :

  12352005

• Target :

  Histamine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/impromidine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N=C(NCCCC1=CN=CN1)NCCSCC2=C(C)N=CN2

• Molecular Formula :

  C14H23N7S

• Molecular Weight :

  321.44

• References & Citations :

  [1]Durant GJ, et al. Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors. Nature. 1978 Nov 23;276 (5686) :403-5. |[2]McIsaac RL, et al. Gastric mucosal blood flow and acid secretory changes in man with impromidine: a new specific histamine-H2-receptor agonist. Gut. 1981 Jul;22 (7) :529-33.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  H2 Receptor

• CAS Number :

  [55273-05-7]