DPP-8/9 probe-1

• UNSPSC Description:

  DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively)[1].

• Target Antigen:

  Dipeptidyl Peptidase

• Type:

  Dye Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dpp-8-9-probe-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CN[C@@]1(C2)C[C@H]3C[C@@](C[C@@H]2C3)(NC(OCCOCCNC4=CC=C([N+]([O-])=O)C5=NON=C54)=O)C1)N(C6)CC7=C6C=CC(F)=C7

• Molecular Weight:

  637.66

• References & Citations:

  [1]Espadinha M, et al. Active site-directed probes targeting dipeptidyl peptidases 8 and 9. Eur J Med Chem. 2024 Apr 15;270:116389.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3020859-80-4