DPP-8/9 probe-1

DPP-8/9 probe-1

• CAS Number: 3020859-80-4
• UNSPSC Description: DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively)[1].
• Target Antigen: Dipeptidyl Peptidase
• Type: Dye Reagents
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/dpp-8-9-probe-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(CN[C@@]1(C2)C[C@H]3C[C@@](C[C@@H]2C3)(NC(OCCOCCNC4=CC=C([N+]([O-])=O)C5=NON=C54)=O)C1)N(C6)CC7=C6C=CC(F)=C7
• Molecular Weight: 637.66
• References & Citations: [1]Espadinha M, et al. Active site-directed probes targeting dipeptidyl peptidases 8 and 9. Eur J Med Chem. 2024 Apr 15;270:116389.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported