DPP-4-IN-1

• Description:

  DPP-4-IN-1 (compound d1) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC50of 49 nM. DPP-4-IN-1 is a structurally analogs of Alogliptin (HY-A0023A) . DPP-4-IN-1 can be used for diabetes research[1].

• UNSPSC:

  12352005

• Target:

  Dipeptidyl Peptidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/dpp-4-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=NC2=CC=NN2C(N3C[C@@H](CCC3)N)=C1CC4=C(C=CC=C4)C#N

• Molecular Formula:

  C19H19ClN6

• Molecular Weight:

  366.85

• References & Citations:

  [1]Shen J, et al. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors. Eur J Med Chem. 2020 Dec 15;208:112850.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  DPP-4

• CAS Number:

  [2215027-46-4]