CDK19 Probe 1

• Description:

  CDK19 Probe 1 (Compound 10c) is a CDK19 inhibitor (IC50: 1.01 μM) and can be used for cancer research[1].

• UNSPSC:

  12171500

• Target:

  CDK

• Type:

  Dye Reagents

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk19-probe-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CN1C=C(C2=CC=C(C3=CN=CC4=CC=CC=C34)C=C2)C=N1)NCCCCCNC(CN5CCN(CCN(CCN(CC5)CC(O)=O)CC(O)=O)CC(O)=O)=O

• Molecular Formula:

  C41H53N9O8

• Molecular Weight:

  799.92

• References & Citations:

  [1]Dai D, et al. Novel CDK19-Targeted Radiotracers: A Potential Design Strategy to Improve the Pharmacokinetics and Tumor Uptake. J Med Chem. 2024 Apr 25;67 (8) :6726-6737.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• Isoform:

  CDK19