DPP-8/9 probe-1

• Target:

  Proteasome|||Others

• Related Pathways:

  Others|||Ubiquitination|||Proteases/Proteasome

• Bioactivity:

  DPP-8/9 probe-1 (compound 20) is a fluorescent probe designed to specifically target and label Dipeptidyl Peptidase DPP8/9, allowing for its visualization through fluorescence microscopy in vitro when active. This compound incorporates a nitrobenzoxadiazole (NBD) tag, demonstrating a high affinity and selectivity for DPP8/9, with significant preference over other S9 family enzymes, evidenced by IC 50 values of 210 nM and 15 nM, respectively. [9] [1]

• Smiles:

  N(C(OCCOCCNC=1C=2C(C(N(=O)=O)=CC1)=NON2)=O)C34CC5(NCC(=O)N6CC=7C(C6)=CC(F)=CC7)CC(C3)CC(C4)C5

• Molecular Formula:

  C31H36FN7O7

• Molecular Weight:

  637.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3020859-80-4