DPP-8/9 probe-1

CAT: 0931-MF-0147501-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0147501-01Size:25 mg
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CAS Number
3020859-80-4
Target
Proteasome|||Others
Related Pathways
Others|||Ubiquitination|||Proteases/Proteasome
Bioactivity
DPP-8/9 probe-1 (compound 20) is a fluorescent probe designed to specifically target and label Dipeptidyl Peptidase DPP8/9, allowing for its visualization through fluorescence microscopy in vitro when active. This compound incorporates a nitrobenzoxadiazole (NBD) tag, demonstrating a high affinity and selectivity for DPP8/9, with significant preference over other S9 family enzymes, evidenced by IC 50 values of 210 nM and 15 nM, respectively. [9] [1]
Smiles
N(C(OCCOCCNC=1C=2C(C(N(=O)=O)=CC1)=NON2)=O)C34CC5(NCC(=O)N6CC=7C(C6)=CC(F)=CC7)CC(C3)CC(C4)C5
Molecular Formula
C31H36FN7O7
Molecular Weight
637.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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