P-gp modulator-5

P-gp modulator-5

• UNSPSC Description: P-gp modulator-5 (compound 25) is a modulator of P-gp and can inhibit the proliferation of multidrug resistant (MDR) tumors. P-gp modulator-5 inhibits the activity of drug efflux pumps in MDR cells, leading to a large accumulation of ROS and altered cell cycle profiles[1].
• Target Antigen: P-glycoprotein
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/p-gp-modulator-5.html
• Smiles: O=C1C=C(C(C2=C(C(C)=[N+](C=C21)[O-])C(OC)=O)=O)NCC3=CC=CC=C3
• Molecular Weight: 352.34
• References & Citations: [1]Discovery of Potent Isoquinolinequinone N-Oxides to Overcome Cancer Multidrug Resistance
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported