P-gp modulator-5

• Description :

  P-gp modulator-5 (compound 25) is a modulator of P-gp and can inhibit the proliferation of multidrug resistant (MDR) tumors. P-gp modulator-5 inhibits the activity of drug efflux pumps in MDR cells, leading to a large accumulation of ROS and altered cell cycle profiles[1].

• UNSPSC :

  12352211

• Target :

  P-glycoprotein

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/p-gp-modulator-5.html

• Smiles :

  O=C1C=C(C(C2=C(C(C)=[N+](C=C21)[O-])C(OC)=O)=O)NCC3=CC=CC=C3

• Molecular Formula :

  C19H16N2O5

• Molecular Weight :

  352.34

• References & Citations :

  [1]Discovery of Potent Isoquinolinequinone N-Oxides to Overcome Cancer Multidrug Resistance

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported