P-gp modulator-5

• UNSPSC Description:

  P-gp modulator-5 (compound 25) is a modulator of P-gp and can inhibit the proliferation of multidrug resistant (MDR) tumors. P-gp modulator-5 inhibits the activity of drug efflux pumps in MDR cells, leading to a large accumulation of ROS and altered cell cycle profiles[1].

• Target Antigen:

  P-glycoprotein

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/p-gp-modulator-5.html

• Smiles:

  O=C1C=C(C(C2=C(C(C)=[N+](C=C21)[O-])C(OC)=O)=O)NCC3=CC=CC=C3

• Molecular Weight:

  352.34

• References & Citations:

  [1]Discovery of Potent Isoquinolinequinone N-Oxides to Overcome Cancer Multidrug Resistance

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported