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P-gp modulator 1

CAT: 0804-HY-112912Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-112912Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P-gp modulator 1 is a high affinity, orally available modulator of P-glycoprotein (Pgp), can reverse the Pgp-mediated multidrug resistance ((MDR) [1].
CAS Number
[2249749-39-9]
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p-gp-modulator-1.html
Solubility
10 mM in DMSO
Smiles
CC(C)(O)[C@H](O1)CC[C@@]1(C)[C@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](NC(CCCCCNC(OC(C)(C)C)=O)=O)CC[C@]5(C)[C@@]4([H])C[C@@H](O)[C@@]32[H]
Molecular Formula
C41H72N2O6
Molecular Weight
689.02
References & Citations
[1]Ren Q, et al. Design, synthesis, and discovery of ocotillol-type amide derivatives as orally available modulators of P-glycoprotein-mediated multidrug resistance. Eur J Med Chem. 2019 Jan 1;161:118-130.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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