P-gp modulator 2

• Description :

  P-gp modulator 2 (Compound 27) is a potent, competitive, allosteric P-glycoprotein (P-gp) modulator[1].

• UNSPSC :

  12352005

• Target :

  P-glycoprotein

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/p-gp-modulator-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=CC=C(C=C1)[C@@H]2C/C(C3=C(O2)C=C(C=C3O)OC)=N\NC4=CC=C(C=N4)Br

• Molecular Formula :

  C22H20BrN3O4

• Molecular Weight :

  470.32

• References & Citations :

  [1]Ferreira RJ, et al. Nitrogen-containing naringenin derivatives for reversing multidrug resistance in cancer. Bioorg Med Chem. 2020 Dec 1;28 (23) :115798.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2987145-05-9]