P-gp modulator-7
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
P-gp modulator-7
Target :
P-gpRelated Pathways :
Neuroscience|||Membrane transporter/Ion channelBioactivity :
P-gp modulator-7 (Compound 9e) is an inhibitor of P-glycoprotein (P-gp) . It uniquely occupies the channel entrance of P-gp in a T-shaped conformation, blocking the peristaltic extrusion mechanism of transmembrane domains TM12 and TM9. This action inhibits P-gp from pumping drugs out of cells and reverses multidrug resistance (MDR) in tumor cells. P-gp modulator-7 shows promise for cancer research.Molecular Formula :
C36H60N2O5Shipping Conditions :
Cool packStorage Temperature :
-20°C
