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P-gp modulator 3

CAT: 0804-HY-146118Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146118Size:1 Each
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Description
P-gp modulator 3 (Compound 37) is a potent, competitive, allosteric P-glycoprotein (P-gp) modulator[1].
CAS Number
2987145-15-1
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p-gp-modulator-3.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(C(O)=C1)C(C[C@H](O2)C3=CC=C(C=C3)OCC(CNC4CCN(CC4)CC5=CC=CC=C5)O)=O
Molecular Formula
C31H36N2O6
Molecular Weight
532.63
References & Citations
[1]Ferreira RJ, et al. Nitrogen-containing naringenin derivatives for reversing multidrug resistance in cancer. Bioorg Med Chem. 2020 Dec 1;28 (23) :115798.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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