P-gp modulator 3

• Description:

  P-gp modulator 3 (Compound 37) is a potent, competitive, allosteric P-glycoprotein (P-gp) modulator[1].

• UNSPSC:

  12352005

• Target:

  P-glycoprotein

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/p-gp-modulator-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC2=C(C(O)=C1)C(C[C@H](O2)C3=CC=C(C=C3)OCC(CNC4CCN(CC4)CC5=CC=CC=C5)O)=O

• Molecular Formula:

  C31H36N2O6

• Molecular Weight:

  532.63

• References & Citations:

  [1]Ferreira RJ, et al. Nitrogen-containing naringenin derivatives for reversing multidrug resistance in cancer. Bioorg Med Chem. 2020 Dec 1;28 (23) :115798.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2987145-15-1]