ASK1-IN-5

• Description:

  ASK1-IN-5 (S-99) is an inhibitor of apoptosis signal-regulated kinase 1 (ASK1) and is useful in the study of autoimmune and neurodegenerative diseases[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H317

• Target:

  Apoptosis; ASK1; MAP3K

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; MAPK/ERK Pathway

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ask1-in-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=CN=C1)NC2=NN3C(NC(C)C)=CC(C(F)(F)F)=CC3=N2

• Molecular Formula:

  C16H15F3N6O

• Molecular Weight:

  364.33

• Precautions:

  H317

• References & Citations:

  [1]Dominique Swinnen, et al.Triazolopyridine compounds and their use as ask inhibitors.WO2009027283A1

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  MAP3K5/ASK1

• CAS Number:

  [1124381-69-6]