ASK1-IN-5

• Description :

  ASK1-IN-5 (S-99) is an inhibitor of apoptosis signal-regulated kinase 1 (ASK1) and is useful in the study of autoimmune and neurodegenerative diseases[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H317

• Target :

  Apoptosis; ASK1; MAP3K

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; MAPK/ERK Pathway

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ask1-in-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC=CN=C1)NC2=NN3C(NC(C)C)=CC(C(F)(F)F)=CC3=N2

• Molecular Formula :

  C16H15F3N6O

• Molecular Weight :

  364.33

• Precautions :

  H317

• References & Citations :

  [1]Dominique Swinnen, et al.Triazolopyridine compounds and their use as ask inhibitors.WO2009027283A1

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MAP3K5/ASK1

• CAS Number :

  [1124381-69-6]