ASK1-IN-8

• Target :

  ASK

• Related Pathways :

  Apoptosis

• Bioactivity :

  ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.

• Smiles :

  O=C1N(C2=NC(=CC=C2)C3=NN=CN3C(C)C)CCN1C4=CC=C(C=C4)N5CCC(C(=O)NC)CC5

• Molecular Formula :

  C26H32N8O2

• Molecular Weight :

  488.585

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2570985-89-4