ASK1-IN-8

CAT: 0931-T206247-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T206247-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2570985-89-4
Target
ASK
Related Pathways
Apoptosis
Bioactivity
ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.
Smiles
O=C1N(C2=NC(=CC=C2)C3=NN=CN3C(C)C)CCN1C4=CC=C(C=C4)N5CCC(C(=O)NC)CC5
Molecular Formula
C26H32N8O2
Molecular Weight
488.585
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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