ASK1-IN-4

• UNSPSC Description:

  ASK1-IN-4 (Compound 17) is an ASK1 inhibitor (IC50=0.2 μM). ASK1-IN-4 interacts with ATP-binding site of ASK1[1].

• Target Antigen:

  Apoptosis; MAP3K

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;MAPK/ERK Pathway

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ask1-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  BrC(C=C1)=CC=C1C2=CC=C(O2)/C=C3C(N(C(S/3)=S)CCCC(O)=O)=O

• Molecular Weight:

  452.34

• References & Citations:

  [1]Starosyla SA,et al. ASK1 pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4418-4423.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1427538-26-8