RegisterLogin

ASK1-IN-3

CAT: 0804-HY-146729Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-146729Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ASK1-IN-3 is a potent and selective ASK1 kinase inhibitor with IC50 of 33.8 nM, as well as inhibits several cell cycle regulating kinases. ASK1-IN-3 has strong HepG2 cancer cells apoptosis induction and potent cell cycle arrest activities[1].
CAS Number
[2426705-19-1]
UNSPSC
12352005
Target
Apoptosis; ASK1; MAP3K
Type
Reference compound
Related Pathways
Apoptosis; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ask1-in-3.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](N1C=NN=C1C2=NC(NC(NC3=NN4C=CC=CC4=C3)=O)=CC=C2)CO
Molecular Formula
C18H18N8O2
Molecular Weight
378.39
References & Citations
[1]Zhang S, Huang C, Lyu X, et al. Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1) . Eur J Med Chem. 2020;195:112277.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP3K5/ASK1

Related Products

CatalogName
HY-173293ASK1-IN-8
HY-176881ASK1-IN-10
HY-176882ASK1-IN-11
HY-179517ASK1-IN-12
HY-133554-01ASK1-IN-1
HY-160939-01ASK1-IN-6
HY-169555ASK1-IN-7
HY-176880ASK1-IN-9
HY-153761ASK1-IN-4
HY-18297ASK1-IN-5

Alternative Products

CatalogName
T61584-01ASK1-IN-3
MBS8565376-01ASK1
MBS3617169-01ASK1-IN-2
MBS8580810-01ASK1 Antibody
507024ASK1 discontinued
MBS517189-01ASK1, Active
T67857-01ASK1-IN-4
AF6549-BPASK1 Peptide

Popular Products