Keap1-Nrf2-IN-17

Keap1-Nrf2-IN-17

• CAS Number: 3042821-85-9
• UNSPSC Description: Keap1-Nrf2-IN-17 (compound 18) is a potent inhibitor of Keap1-Nrf2 protein-protein interaction[1].
• Target Antigen: Keap1-Nrf2
• Type: Reference compound
• Related Pathways: NF-κB
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/keap1-nrf2-in-17.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)CN(S(=O)(C1=CC=C(C)C=C1)=O)C2=C3C(C=CC=C3)=C(N(S(=O)(C4=CC=C(C)C=C4)=O)CC(O)=O)C=C2OCC(O)=O
• Molecular Weight: 656.68
• References & Citations: [1]Sumi Lee, et al. Structural modification of C2-substituents on 1,4-bis(arylsulfonamido)benzene or naphthalene-N,N′-diacetic acid derivatives as potent inhibitors of the Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2023 Dec 27:265:116104.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported