Products for Research Use Only
RegisterLogin

Antitumor agent-136

CAT: 0804-HY-161180-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-161180-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Antitumor Agent-136 (Compound 17) is a potent broad-spectrum antitumor agent and a NAMPT inhibitor with an IC50 of 9.5 nM. Antitumor Agent-136 can reduce the levels of intracellular and extracellular NAMPT protein through the ubiquitin proteasome pathway, thus achieving tumor inhibition[1].
CAS Number
2484876-94-8
UNSPSC
12352005
Target
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-136.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C=C1)CN2CCN(CC2)S(=O)(C3=CC=C(C=C3)NC(NCC4=CN=CC=C4)=S)=O)NCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N5[C@@H](C[C@H](C5)O)C(N[C@H](C6=CC=C(C7=C(N=CS7)C)C=C6)C)=O)=O)=O
Molecular Formula
C58H76N10O11S3
Molecular Weight
1185.48
References & Citations
[1], et al. NAMPT protein degradation targeting chimera and preparation method and application thereof. China. CN111454327. 2020-07028.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-162128Antitumor agent-130
HY-161425Antitumor agent-149
HY-155034Antitumor agent-102
HY-151292Antitumor agent-74
HY-116447-01Antitumor agent-159
HY-149717Antitumor agent-122
HY-115948Antitumor agent-46
HY-152537Antitumor agent-84
HY-128776Antitumor agent-19
HY-163691Antitumor agent-163

Alternative Products

CatalogName
T10342-01Antitumor agent-2
T211211-01Antitumor agent-203
T209984-01Antitumor agent-156
T209806-01Antitumor agent-151
T209096-01Antitumor agent-131
T206452-01Antitumor agent-200
T205444-01Antitumor agent-198
T200846-01Antitumor agent-188
T89076-01Antitumor agent-175
T88732-01Antitumor agent-164

Popular Products