CNB-001

CAT: 0931-T86070-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T86070-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1019110-87-2
Target
Lipoxygenase
Related Pathways
Metabolism
Bioactivity
CNB-001 is a potent inhibitor of 5-lipoxygenase (5-LOX) that reduces 5-LOX expression while enhancing proteasome activity. It also increases phosphorylation of eIF2? and levels of HSP90 and ATF4 in Alzheimer's disease transgenic mice, thereby limiting soluble A? and ubiquitinated aggregated protein accumulation. Additionally, CNB-001 maintains synapse-associated protein expression and improves memory, making it a valuable compound for Alzheimer's disease research [1].
Smiles
C(=C/C1=CC(OC)=C(O)C=C1)\C=2N(N=C(/C=C/C3=CC(OC)=C(O)C=C3)C2)C4=CC=CC=C4
Molecular Formula
C27H24N2O4
Molecular Weight
440.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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