CNB-001

• Target :

  Lipoxygenase

• Related Pathways :

  Metabolism

• Bioactivity :

  CNB-001 is a potent inhibitor of 5-lipoxygenase (5-LOX) that reduces 5-LOX expression while enhancing proteasome activity. It also increases phosphorylation of eIF2? and levels of HSP90 and ATF4 in Alzheimer's disease transgenic mice, thereby limiting soluble A? and ubiquitinated aggregated protein accumulation. Additionally, CNB-001 maintains synapse-associated protein expression and improves memory, making it a valuable compound for Alzheimer's disease research [1].

• Smiles :

  C(=C/C1=CC(OC)=C(O)C=C1)\C=2N(N=C(/C=C/C3=CC(OC)=C(O)C=C3)C2)C4=CC=CC=C4

• Molecular Formula :

  C27H24N2O4

• Molecular Weight :

  440.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1019110-87-2