Nrf2/HO-1 activator 1

Nrf2/HO-1 activator 1

• CAS Number: 2883506-60-1
• UNSPSC Description: Nrf2/HO-1 activator 1 (Compound 24) is a potent Nrf2/HO-1 activator, neuroprotective agent. Nrf2/HO-1 activator 1 shows neuroprotective and antioxidant activities. Nrf2/HO-1 activator 1 can be used in Parkinson's disease (PD) research[1].
• Target Antigen: Akt; ERK; JNK; Keap1-Nrf2; Reactive Oxygen Species
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB;PI3K/Akt/mTOR;Stem Cell/Wnt
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/nrf2-ho-1-activator-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(C2=CC=C(OC)C=C2)=COC3=C1C4=C(C=CC(C)(C)O4)C(O)=C3
• Molecular Weight: 350.36
• References & Citations: [1]Qili Lu, et al. Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling. Eur J Med Chem. 2022 Nov 15;242:114692.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported