Nrf2 activator-1

Nrf2 activator-1

• CAS Number: 2230697-41-1
• UNSPSC Description: Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1)[1].
• Target Antigen: Keap1-Nrf2
• Type: Reference compound
• Related Pathways: NF-κB
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/nrf2-activator-1.html
• Solubility: 10 mM in DMSO
• Smiles: CCOC(C[C@@H](C1=CC(CN2S(=O)(C3=CC=CC=C3O[C@@H](C2)C)=O)=C(C=C1)C)C4=CC(OC)=C(N(N=N5)C)C5=C4)=O
• Molecular Weight: 578.68
• References & Citations: [1]James Francis Callahan, et al. Bisaryl amides as nrf2 regulators. Patent WO2018109647A1.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported