Nrf2 activator-1

• UNSPSC Description:

  Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1)[1].

• Target Antigen:

  Keap1-Nrf2

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/nrf2-activator-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCOC(C[C@@H](C1=CC(CN2S(=O)(C3=CC=CC=C3O[C@@H](C2)C)=O)=C(C=C1)C)C4=CC(OC)=C(N(N=N5)C)C5=C4)=O

• Molecular Weight:

  578.68

• References & Citations:

  [1]James Francis Callahan, et al. Bisaryl amides as nrf2 regulators. Patent WO2018109647A1.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  2230697-41-1