Nrf2 activator-7

• UNSPSC Description:

  Nrf2 activator-7 (Compound 12b) is a potent Nrf2 activator and significantly activates the Nrf2 signaling pathway.

• Target Antigen:

  Keap1-Nrf2

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/nrf2-activator-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC=C(C=C1)C2=C(C3=C(C(N(S(=O)(C4=CC=C(C=C4)OC)=O)CC(O)=O)=C2)C=CC=C3)N(S(=O)(C5=CC=C(C=C5)OC)=O)CC(O)=O

• Molecular Weight:

  720.77

• References & Citations:

  [1]Abed DA, et al. Optimization of the C2 substituents on the 1,4-bis(arylsulfonamido)naphthalene-N,N'-diacetic acid scaffold for better inhibition of Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2023 Apr 5;252:115302.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2456295-39-7