Nrf2 activator-7

Nrf2 activator-7

• CAS Number: 2456295-39-7
• UNSPSC Description: Nrf2 activator-7 (Compound 12b) is a potent Nrf2 activator and significantly activates the Nrf2 signaling pathway.
• Target Antigen: Keap1-Nrf2
• Type: Reference compound
• Related Pathways: NF-κB
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/nrf2-activator-7.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=C(C=C1)C2=C(C3=C(C(N(S(=O)(C4=CC=C(C=C4)OC)=O)CC(O)=O)=C2)C=CC=C3)N(S(=O)(C5=CC=C(C=C5)OC)=O)CC(O)=O
• Molecular Weight: 720.77
• References & Citations: [1]Abed DA, et al. Optimization of the C2 substituents on the 1,4-bis(arylsulfonamido)naphthalene-N,N'-diacetic acid scaffold for better inhibition of Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2023 Apr 5;252:115302.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported