RIPK2-IN-3

• Description:

  RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor. RIPK2-IN-3 inhibits recombinant truncated RIPK2 with an IC50 of 6.39 μM. RIPK2-IN-3 can be used for research of inflammation and cancer[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  RIP kinase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ripk2-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC=CC(C2=NC=CN2C)=C1)C3=CC=C(C)C(NC(C4=CC=CC=C4)=O)=C3

• Molecular Formula:

  C25H22N4O2

• Molecular Weight:

  410.47

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Shairaz BAKSH, et al. Ripk2 inhibitors. WO2019161495.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1290490-78-6