RIPK2 IN 10W

• Target:

  NOD-like Receptor (NLR) |||RIP kinase|||TNF

• Related Pathways:

  Apoptosis|||Immunology/Inflammation|||NF-?B

• Bioactivity:

  The IC50 value of RIPK2 IN 10W for RIPK2 is 0.6 nM, which is more than 50000 times higher than RIPK1 (IC50>30 ? M) . RIPK2 IN 10W has high kinase selectivity, inhibits RIPK2, and prevents NOD induced cytokine production after stimulation with muramyl dipeptide (MDP) . RIPK2 as a therapeutic target has shown potential in treating inflammatory bowel disease.

• Smiles:

  NC1=C2C(=CN(C2=NC=N1)[C@H]3CC[C@@H](N)CC3)C4=C(F)C=C(C)C=C4

• Molecular Formula:

  C19H22FN5

• Molecular Weight:

  339.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2789711-40-4