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RIPK2 IN 10W

CAT: 0931-T204013-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204013-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2789711-40-4
Target
NOD-like Receptor (NLR), RIP kinase, TNF
Related Pathways
Apoptosis, Immunology/Inflammation, NF-κB
Bioactivity
The IC50 value of RIPK2 IN 10W for RIPK2 is 0.6 nM, which is more than 50000 times higher than RIPK1 (IC50>30 μ M) . RIPK2 IN 10W has high kinase selectivity, inhibits RIPK2, and prevents NOD induced cytokine production after stimulation with muramyl dipeptide (MDP) . RIPK2 as a therapeutic target has shown potential in treating inflammatory bowel disease.
Smiles
NC1=C2C(=CN(C2=NC=N1)[C@H]3CC[C@@H](N)CC3)C4=C(F)C=C(C)C=C4
Molecular Formula
C19H22FN5
Molecular Weight
339.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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