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RIPK2/3-IN-1

CAT: 0931-T79352-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79352-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
RIP kinase
Related Pathways
Apoptosis, NF-κB
Bioactivity
RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3. Additionally, in a 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay, RIPK2/3-IN-1 demonstrates an IC50 value of 14 ± 4 nM against RIPK2 [1].
Molecular Formula
C24H16N4O2S2
Molecular Weight
456.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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