RIPK2-IN-4

• UNSPSC Description:

  RIPK2-IN-4 is a potent and specific RIPK2 inhibitor with an IC50 value of 5 nM[1].

• Target Antigen:

  RIP kinase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ripk2-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C1(C2=CC3=C(S2)N=CN=C3NC4=CC5=C(SC=N5)C=C4)=NNC=C1

• Molecular Weight:

  350.42

• References & Citations:

  [1]Mbilo Misehe, et al. Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors. Bioorg Med Chem Lett .2024 Jan 1:97:129567

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported