RIPK2-IN-2

• UNSPSC Description:

  RIPK2-IN-2 (example 25) is a RIP2 kinase PROTAC inhibitor. RIPK2-IN-2 can block RIP2-dependent proinflammatory signaling, regulated RIP2 kinase activity in auto inflammatory diseases[1].

• Target Antigen:

  PROTACs; RIP kinase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;PROTAC

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ripk2-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCC(CC1)[C@H](NC([C@H](C)NC)=O)C(N2[C@@](C3=NC(C(C4=CC=C(C=C4)F)=O)=CS3)([H])CCC2)=O)C5=CN=C(N=C5)N(CC6)CCN6CCOC(C(S(C(C)(C)C)(=O)=O)=C7)=CC8=C7C(NC9=NNC(C)=C9C)=NC=N8

• Molecular Weight:

  1093.30

• References & Citations:

  [1]Conjugates comprising ripk2 inhibitors, WO2017182418 (example 25)

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2143956-20-9