Exatecan Intermediate 4

• Description:

  Exatecan Intermediate 4 (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631) . Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Payload; Drug Intermediate

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/exatecan-intermediate-4.html

• Purity:

  99.31

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C2CCC(C(C2=C(C=C1F)N)=O)N.Cl

• Molecular Formula:

  C11H14ClFN2O

• Molecular Weight:

  244.70

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Ao Li, et al. Anti-tumor compound and use thereof. China, WO2024109949A1. 2024-05-30.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Camptothecins

• CAS Number:

  [2436720-50-0]