Exatecan Intermediate 6

• Target :

  ADC Cytotoxin

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  Exatecan Intermediate 6 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I inhibitor with an IC50 value of 2.2 ?M (0.975 ?g/mL), utilized in cancer research. Additionally, Exatecan Intermediate 6 is employed in the preparation of Antibody-Drug Conjugates (ADCs) .

• Smiles :

  O=C(NC1=CC(F)=C(C2=C1C(=O)CCC2)C)C

• Molecular Formula :

  C13H14FNO2

• Molecular Weight :

  235.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  143655-58-7