Exatecan Intermediate 5

• Target:

  ADC Cytotoxin

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  Exatecan Intermediate 5 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I (topoisomerase I) inhibitor with an IC50 of 2.2 ?M (0.975 ?g/mL), utilized in cancer research. This intermediate is also employed in the production of Antibody-Drug Conjugates (ADCs) .

• Smiles:

  O=C(NC1=CC(F)=C(C2=C1C(=O)C(NC(=O)C)CC2)C)C

• Molecular Formula:

  C15H17FN2O3

• Molecular Weight:

  292.31

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  143655-70-3