Exatecan Intermediate 5

• Target :

  ADC Cytotoxin

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  Exatecan Intermediate 5 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I (topoisomerase I) inhibitor with an IC50 of 2.2 ?M (0.975 ?g/mL), utilized in cancer research. This intermediate is also employed in the production of Antibody-Drug Conjugates (ADCs) .

• Smiles :

  O=C(NC1=CC(F)=C(C2=C1C(=O)C(NC(=O)C)CC2)C)C

• Molecular Formula :

  C15H17FN2O3

• Molecular Weight :

  292.31

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  143655-70-3