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Exatecan intermediate 8

CAT: 0931-T208344-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T208344-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ADC Cytotoxin, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
Exatecanintermediate 8 serves as an intermediate in the synthesis of Exatecan. Exatecan (DX-8951) is a commonly used cytotoxin component in ADC (Antibody-Drug Conjugate) preparation, and it functions as an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
Molecular Formula
C30H34FN3O9S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C