FA4-Cu

• Description :

  FA4-Cu is a complex of the potent pancreatic cancer inhibitor FA4 and Cu (II) that induces apoptosis via ER and mitochondrial stress[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/fa4-cu.html

• Smiles :

  CN(C1=N[N]2=C(C3=O[Cu]2(S1)Cl)C4=CC=CC=C4N3CCCCN5CCC6(CC5)C7=C(CO6)C=CC=C7)C.Cl

• Molecular Formula :

  C27H33Cl2CuN5O2S

• Molecular Weight :

  626.10

• References & Citations :

  [1]Barbanente A, et al. First-In-Class Thiosemicarbazone Metal Complexes Targeting the Sigma-2 Receptor (S2R) as an Innovative Strategy against Pancreatic Cancer. J Med Chem. 2024 Nov 28;67 (22) :20118-20134.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported