CU-CPD107

CAT: 0804-HY-147310-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-147310-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

CU-CPD107 is a potent, selective toll-like receptor 8 (TLR 8) agonist. CU-CPD107 inhibits TLR8 signaling. CU-CPD107 converts to synergistic agonist activities in the presence of ssRNA and induces TLR8 signaling. CU-CPD107 inhibits proinflammatory factor expression and avoids immune responses in the presence of ssRNA[1].

CAS Number

2573912-32-8

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cu-cpd107.html

Purity

98.07

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

IC1=C(C2=CC=CC=C2)N(CC(C)(C)O)C(COCC)=N1

Molecular Formula

C16H21IN2O2

Molecular Weight

400.25

References & Citations

[1]Yang Y, et, al. Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a (nta) gonists. Nat Commun. 2021 Jul 16;12 (1) :4351.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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